A Smart and Sexy Comedy!

Karly Hert (Katherine Heigl) has spent the last ten years selling drugs...legally, that is. She works for one of corporate America's darlings, the pharmaceutical industry. Karly has it all - a big salary, a company car, a closet full of hot business suits and a growing pit in her stomach...

Everything changes when she meets sexy Zach Danner (Lucian McAfee), a down-to-earth guy. Sparks fly! As their relationship heats up, he encourages Karly to walk her talk and leave her empty job. Karly devises a plan to get out - she begins being brutally honest with physicians about her drugs' "benefits." Ironically, her sales go through the roof and she is once again wooed by the seductive golden handcuffs.

Somehow leaving is never quite as easy as it seems...

SIDE EFFECTS stars Grey's Anatomy's hottest intern, Katherine Heigl - it's the perfect prescription for a new comedy!

*The DVD contains exclusive behind-the-scenes footage, director's commentary, and more.

"The timing of Side Effects couldn't be better." USA Today

"Biting"  CNN

"Savagely Funny" British Medical Journal

"Drop dead fascinating" Healthy Talk Radio